4eaq

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[[Image:4eaq.png|left|200px]]
 
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{{STRUCTURE_4eaq| PDB=4eaq | SCENE= }}
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==Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate==
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<StructureSection load='4eaq' size='340' side='right'caption='[[4eaq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4eaq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eaq OCA], [https://pdbe.org/4eaq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eaq RCSB], [https://www.ebi.ac.uk/pdbsum/4eaq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eaq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).
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===Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate===
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==See Also==
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*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4eaq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAQ OCA].
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[[Category: Large Structures]]
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[[Category: DTMP kinase]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson WF]]
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[[Category: Babnigg, G.]]
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[[Category: Babnigg G]]
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[[Category: Filippova, E V.]]
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[[Category: Filippova EV]]
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[[Category: Jedrzejczak, R.]]
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[[Category: Jedrzejczak R]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Kiryukhina, O.]]
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[[Category: Kiryukhina O]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Minasov G]]
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[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors.]]
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[[Category: Rubin E]]
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[[Category: Minasov, G.]]
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[[Category: Sacchettini J]]
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[[Category: Rubin, E.]]
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[[Category: Shuvalova L]]
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[[Category: Sacchettini, J.]]
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[[Category: Shuvalova, L.]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Mtbi]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Thymidylate kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate

PDB ID 4eaq

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