4ew4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:10, 14 March 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4ew4.png|left|200px]]
 
-
{{STRUCTURE_4ew4| PDB=4ew4 | SCENE= }}
+
==mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar==
 +
<StructureSection load='4ew4' size='340' side='right'caption='[[4ew4]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4ew4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EW4 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.791&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ew4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ew4 OCA], [https://pdbe.org/4ew4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ew4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ew4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ew4 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MBD4_MOUSE MBD4_MOUSE] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
-
===mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar===
+
==See Also==
-
 
+
*[[Methyl CpG binding protein 3D structures|Methyl CpG binding protein 3D structures]]
-
{{ABSTRACT_PUBMED_22740654}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
[[4ew4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EW4 OCA].
+
[[Category: Mus musculus]]
-
 
+
[[Category: Synthetic construct]]
-
==Reference==
+
[[Category: Cheng X]]
-
<ref group="xtra">PMID:022740654</ref><references group="xtra"/>
+
[[Category: Hashimoto H]]
-
[[Category: Cheng, X.]]
+
[[Category: Zhang X]]
-
[[Category: Hashimoto, H.]]
+
-
[[Category: Zhang, X.]]
+
-
[[Category: Dna glycosylase]]
+
-
[[Category: Helix-hairpin-helix]]
+
-
[[Category: Hydrolase-dna complex]]
+
-
[[Category: N-glycosidic bond]]
+
-
[[Category: Stable intermediate]]
+

Current revision

mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar

PDB ID 4ew4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ew4"
Personal tools