3tt4

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[[Image:3tt4.png|left|200px]]
 
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{{STRUCTURE_3tt4| PDB=3tt4 | SCENE= }}
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==Human MMP8 in complex with L-glutamate motif inhibitor==
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<StructureSection load='3tt4' size='340' side='right'caption='[[3tt4]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3tt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TT4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=E1S:N~2~-{3-[4-(5-METHYLTHIOPHEN-2-YL)PHENYL]PROPANOYL}-L-ALPHA-GLUTAMINE'>E1S</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tt4 OCA], [https://pdbe.org/3tt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tt4 RCSB], [https://www.ebi.ac.uk/pdbsum/3tt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tt4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens.
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===Human MMP8 in complex with L-glutamate motif inhibitor===
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==See Also==
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*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
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{{ABSTRACT_PUBMED_22689580}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[3tt4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TT4 OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Neutrophil collagenase]]
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[[Category: Large Structures]]
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[[Category: Beau, F.]]
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[[Category: Beau F]]
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[[Category: Czarny, B.]]
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[[Category: Czarny B]]
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[[Category: Devel, L.]]
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[[Category: Devel L]]
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[[Category: Dive, V.]]
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[[Category: Dive V]]
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[[Category: Stura, E A.]]
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[[Category: Stura EA]]
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[[Category: Vera, L.]]
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[[Category: Vera L]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Metzincin]]
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[[Category: Potent inhibitor]]
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[[Category: Pseudo dipeptide]]
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[[Category: Zinc metalloprotease]]
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Current revision

Human MMP8 in complex with L-glutamate motif inhibitor

PDB ID 3tt4

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OCA

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