This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4fix

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:16, 1 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4fix.png|left|200px]]
 
-
{{STRUCTURE_4fix| PDB=4fix | SCENE= }}
+
==Crystal Structure of GlfT2==
-
 
+
<StructureSection load='4fix' size='340' side='right'caption='[[4fix]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
-
===Crystal Structure of GlfT2===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4fix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FIX FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22707726}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fix OCA], [https://pdbe.org/4fix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fix RCSB], [https://www.ebi.ac.uk/pdbsum/4fix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fix ProSAT]</span></td></tr>
-
[[4fix]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIX OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/GLFT2_MYCTU GLFT2_MYCTU] Involved in the polymerization of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacteria cell wall, through successively beta-D-(1->5) and beta-D-(1->6)-galactofuranosyltransferases activities. It transfers the galactofuranosyl (Galf) unit from UDP-galactofuranosyl (UDP-Galf) onto the galactofuranosyl-rhamnosyl-GlcNAc-pyrophosphoryl-undecaprenyl (Galf-Rha-GlcNAc-PP-C55), yielding polygalactofuranosyl-rhamnosyl-GlcNAc-pyrophosphoryl-undecaprenyl ((Galf)x-Rha-GlcNAc-PP-C55). It is able to transfer Galf onto beta-D-(1->5) or beta-D-(1->6) linked acceptor, but has a stronger affinity for beta-D-(1->6) acceptor.<ref>PMID:10934214</ref> <ref>PMID:11304545</ref> <ref>PMID:16704275</ref> <ref>PMID:18055597</ref> <ref>PMID:18423586</ref> <ref>PMID:19571009</ref>
-
<ref group="xtra">PMID:022707726</ref><references group="xtra"/>
+
== References ==
-
[[Category: Mycobacterium tuberculosis h37rv]]
+
<references/>
-
[[Category: Lowary, T L.]]
+
__TOC__
-
[[Category: Ng, K K.S.]]
+
</StructureSection>
-
[[Category: Wheatley, R W.]]
+
[[Category: Large Structures]]
-
[[Category: Zheng, R B.]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Carbohydrate binding]]
+
[[Category: Lowary TL]]
-
[[Category: Cazy gt-2 family]]
+
[[Category: Ng KKS]]
-
[[Category: Galactofuranosyltransferase]]
+
[[Category: Wheatley RW]]
-
[[Category: Glycosyltransferase]]
+
[[Category: Zheng RB]]
-
[[Category: Membrane]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal Structure of GlfT2

PDB ID 4fix

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4fix"
Personal tools