4hhs

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'''Unreleased structure'''
 
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The entry 4hhs is ON HOLD
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==Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana)==
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<StructureSection load='4hhs' size='340' side='right'caption='[[4hhs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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Authors: Goulah, C.C., Zhu, G., Koszelak-Rosenblum, M., Malkowski, M.G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4hhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HHS FirstGlance]. <br>
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Description: Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hhs OCA], [https://pdbe.org/4hhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hhs RCSB], [https://www.ebi.ac.uk/pdbsum/4hhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hhs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DOX1_ARATH DOX1_ARATH] Alpha-dioxygenase that catalyzes the primary oxygenation of fatty acids into oxylipins. Mediates a protection against oxidative stress and cell death, probably by generating some lipid-derived molecules. Promotes local and systemic plant defense in a salicylic acid (SA)-dependent manner, including the establishment of systemic acquired resistance (SAR) in response to incompatible interaction. Involved in a negative regulation of abscisic acid (ABA)-mediated signaling pathway.<ref>PMID:12060227</ref> <ref>PMID:10455113</ref> <ref>PMID:22199234</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Goulah CC]]
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[[Category: Koszelak-Rosenblum M]]
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[[Category: Malkowski MG]]
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[[Category: Zhu G]]

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Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana)

PDB ID 4hhs

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