1lbh

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[[Image:1lbh.png|left|200px]]
 
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{{STRUCTURE_1lbh| PDB=1lbh | SCENE= }}
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==INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG==
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<StructureSection load='1lbh' size='340' side='right'caption='[[1lbh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lbh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBH FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8638105}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPT:ISOPROPYL-1-BETA-D-THIOGALACTOSIDE'>IPT</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbh OCA], [https://pdbe.org/1lbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbh RCSB], [https://www.ebi.ac.uk/pdbsum/1lbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbh ProSAT]</span></td></tr>
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[[1lbh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBH OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lbh ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Lac repressor|Lac repressor]]
*[[Lac repressor|Lac repressor]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008638105</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Chang, G.]]
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[[Category: Large Structures]]
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[[Category: Horton, N C.]]
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[[Category: Chang G]]
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[[Category: Kercher, M A.]]
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[[Category: Horton NC]]
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[[Category: Lewis, M.]]
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[[Category: Kercher MA]]
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[[Category: Lu, P.]]
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[[Category: Lewis M]]
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[[Category: Pace, H C.]]
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[[Category: Lu P]]
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[[Category: Dna-binding]]
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[[Category: Pace HC]]
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[[Category: Repressor]]
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[[Category: Transcription regulation]]
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Current revision

INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG

PDB ID 1lbh

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