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3rmc

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[[Image:3rmc.png|left|200px]]
 
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{{STRUCTURE_3rmc| PDB=3rmc | SCENE= }}
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==Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol==
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<StructureSection load='3rmc' size='340' side='right'caption='[[3rmc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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===Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rmc]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RMC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21781974}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTG:(5R,6S)-5,6-DIHYDRO-5,6-DIHYDROXYTHYMIDINE-5-MONOPHOSPHATE'>CTG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rmc OCA], [https://pdbe.org/3rmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rmc RCSB], [https://www.ebi.ac.uk/pdbsum/3rmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rmc ProSAT]</span></td></tr>
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[[3rmc]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RMC OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021781974</ref><ref group="xtra">PMID:017210917</ref><references group="xtra"/>
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[[Category: Escherichia phage RB69]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Enterobacteria phage rb69]]
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[[Category: Aller P]]
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[[Category: Aller, P.]]
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[[Category: Doublie S]]
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[[Category: Doublie, S.]]
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[[Category: Duclos S]]
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[[Category: Duclos, S.]]
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[[Category: Wallace SS]]
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[[Category: Wallace, S S.]]
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[[Category: Dna lesion]]
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[[Category: Protein-dna complex]]
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[[Category: Thymine glycol]]
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[[Category: Transferase-dna complex]]
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Current revision

Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol

PDB ID 3rmc

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