3u57

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[[Image:3u57.png|left|200px]]
 
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{{STRUCTURE_3u57| PDB=3u57 | SCENE= }}
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==Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity==
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<StructureSection load='3u57' size='340' side='right'caption='[[3u57]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
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===Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3u57]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U57 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22004291}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DH8:(2BETA,7BETA,16S,17R,19E,21BETA)-21-(BETA-D-GLUCOPYRANOSYLOXY)-2,7-DIHYDRO-7,17-CYCLOSARPAGAN-17-YL+ACETATE'>DH8</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u57 OCA], [https://pdbe.org/3u57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u57 RCSB], [https://www.ebi.ac.uk/pdbsum/3u57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u57 ProSAT]</span></td></tr>
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[[3u57]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U57 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref>
==See Also==
==See Also==
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*[[Beta-glucosidase|Beta-glucosidase]]
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*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:022004291</ref><references group="xtra"/>
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__TOC__
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[[Category: Raucaffricine beta-glucosidase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rauvolfia serpentina]]
[[Category: Rauvolfia serpentina]]
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[[Category: Barleben, L.]]
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[[Category: Barleben L]]
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[[Category: Lin, H.]]
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[[Category: Lin H]]
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[[Category: Panjikar, S.]]
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[[Category: Panjikar S]]
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[[Category: Rajendran, C.]]
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[[Category: Rajendran C]]
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[[Category: Ruppert, M.]]
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[[Category: Ruppert M]]
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[[Category: Stoeckigt, J.]]
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[[Category: Stoeckigt J]]
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[[Category: Wang, M.]]
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[[Category: Wang M]]
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[[Category: Xia, L.]]
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[[Category: Xia L]]
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[[Category: Alkaloid glucosidase]]
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[[Category: Hydrolase]]
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Current revision

Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity

PDB ID 3u57

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