1r6o

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[[Image:1r6o.png|left|200px]]
 
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{{STRUCTURE_1r6o| PDB=1r6o | SCENE= }}
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==ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS==
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<StructureSection load='1r6o' size='340' side='right'caption='[[1r6o]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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===ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1r6o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R6O FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15037248}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=Y1:YTTRIUM+ION'>Y1</scene>, <scene name='pdbligand=YBT:BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE+YTTRIUM'>YBT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r6o OCA], [https://pdbe.org/1r6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r6o RCSB], [https://www.ebi.ac.uk/pdbsum/1r6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r6o ProSAT]</span></td></tr>
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[[1r6o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6O OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CLPS_ECOLI CLPS_ECOLI] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r6o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r6o ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Clp Protease|Clp Protease]]
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*[[ATP-dependent Clp protease adaptor protein 3D structures|ATP-dependent Clp protease adaptor protein 3D structures]]
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:015037248</ref><references group="xtra"/>
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Esser, L.]]
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[[Category: Large Structures]]
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[[Category: Guo, F.]]
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[[Category: Esser L]]
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[[Category: Maurizi, M R.]]
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[[Category: Guo F]]
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[[Category: Singh, S K.]]
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[[Category: Maurizi MR]]
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[[Category: Xia, D.]]
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[[Category: Singh SK]]
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[[Category: Aaa+]]
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[[Category: Xia D]]
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[[Category: Binding mechanism]]
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[[Category: Clpa]]
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[[Category: Clp]]
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[[Category: Crystal]]
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[[Category: Hydrolase]]
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[[Category: N-terminal domain]]
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Current revision

ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS

PDB ID 1r6o

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