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2ats

From Proteopedia

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[[Image:2ats.png|left|200px]]
 
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{{STRUCTURE_2ats| PDB=2ats | SCENE= }}
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==Dihydrodipicolinate synthase co-crystallised with (S)-lysine==
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<StructureSection load='2ats' size='340' side='right'caption='[[2ats]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Dihydrodipicolinate synthase co-crystallised with (S)-lysine===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2ats]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ATS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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[[2ats]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATS OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ats FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ats OCA], [https://pdbe.org/2ats PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ats RCSB], [https://www.ebi.ac.uk/pdbsum/2ats PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ats ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DAPA_ECOLI DAPA_ECOLI] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<ref>PMID:20503968</ref> <ref>PMID:8993314</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/2ats_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ats ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Dihydrodipicolinate Synthase|Dihydrodipicolinate Synthase]]
 
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
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[[Category: Dihydrodipicolinate synthase]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Devenish, S R.A.]]
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[[Category: Large Structures]]
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[[Category: Dobson, R C.J.]]
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[[Category: Devenish SRA]]
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[[Category: Gerrard, J A.]]
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[[Category: Dobson RCJ]]
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[[Category: Jameson, G B.]]
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[[Category: Gerrard JA]]
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[[Category: Dhdp]]
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[[Category: Jameson GB]]
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[[Category: Dihydrodipicolinate synthase]]
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[[Category: Inhibition]]
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[[Category: Lyase]]
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[[Category: Lysine]]
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Current revision

Dihydrodipicolinate synthase co-crystallised with (S)-lysine

PDB ID 2ats

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