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1ihu

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[[Image:1ihu.png|left|200px]]
 
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{{STRUCTURE_1ihu| PDB=1ihu | SCENE= }}
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==CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE IN COMPLEX WITH MG-ADP-ALF3==
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<StructureSection load='1ihu' size='340' side='right'caption='[[1ihu]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE IN COMPLEX WITH MG-ADP-ALF3===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ihu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IHU FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11395509}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AF3:ALUMINUM+FLUORIDE'>AF3</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TAS:TRIHYDROXYARSENITE(III)'>TAS</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ihu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ihu OCA], [https://pdbe.org/1ihu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ihu RCSB], [https://www.ebi.ac.uk/pdbsum/1ihu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ihu ProSAT]</span></td></tr>
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[[1ihu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHU OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARSA1_ECOLX ARSA1_ECOLX] Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/1ihu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ihu ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ATPase|ATPase]]
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*[[ATPase 3D structures|ATPase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011395509</ref><references group="xtra"/>
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[[Category: Arsenite-transporting ATPase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Gatti, D L.]]
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[[Category: Large Structures]]
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[[Category: Radaev, S.]]
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[[Category: Gatti DL]]
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[[Category: Rosen, B P.]]
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[[Category: Radaev S]]
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[[Category: Zhou, T.]]
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[[Category: Rosen BP]]
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[[Category: Adp]]
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[[Category: Zhou T]]
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[[Category: Aluminum fluoride]]
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[[Category: Arsa atpase]]
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[[Category: Atp binding site]]
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[[Category: Hydrolase]]
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Current revision

CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE IN COMPLEX WITH MG-ADP-ALF3

PDB ID 1ihu

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