3sx3

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[[Image:3sx3.png|left|200px]]
 
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{{STRUCTURE_3sx3| PDB=3sx3 | SCENE= }}
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==Crystal structure of AABB+UDP+Gal with glycerol as the cryoprotectant==
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<StructureSection load='3sx3' size='340' side='right'caption='[[3sx3]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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===Crystal structure of AABB+UDP+Gal with glycerol as the cryoprotectant===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SX3 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22349229}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sx3 OCA], [https://pdbe.org/3sx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sx3 RCSB], [https://www.ebi.ac.uk/pdbsum/3sx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sx3 ProSAT]</span></td></tr>
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[[3sx3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX3 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
==See Also==
==See Also==
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*[[Galactosyltransferase|Galactosyltransferase]]
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022349229</ref><references group="xtra"/>
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[[Category: Fucosylgalactoside 3-alpha-galactosyltransferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Evans, S V.]]
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[[Category: Large Structures]]
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[[Category: Johal, A R.]]
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[[Category: Evans SV]]
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[[Category: Abo rossmann fold]]
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[[Category: Johal AR]]
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[[Category: Blood group antigen]]
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[[Category: Glycoprotein]]
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[[Category: Manganese]]
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[[Category: Metal-binding]]
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[[Category: Retaining glycosyltransferase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of AABB+UDP+Gal with glycerol as the cryoprotectant

PDB ID 3sx3

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