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1l9g
From Proteopedia
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| - | [[Image:1l9g.png|left|200px]] | ||
| - | + | ==CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA== | |
| - | + | <StructureSection load='1l9g' size='340' side='right'caption='[[1l9g]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1l9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L9G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[1l9g]] is a 1 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9g OCA], [https://pdbe.org/1l9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l9g RCSB], [https://www.ebi.ac.uk/pdbsum/1l9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9g ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1l9g TOPSAN]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UDGA_THEMA UDGA_THEMA] Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA.<ref>PMID:10339434</ref> <ref>PMID:11267830</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/1l9g_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l9g ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[DNA | + | *[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
| - | [[Category: Almo | + | [[Category: Almo SC]] |
| - | [[Category: Bresnik | + | [[Category: Bresnik A]] |
| - | [[Category: Burley | + | [[Category: Burley SK]] |
| - | [[Category: Chance | + | [[Category: Chance MR]] |
| - | [[Category: Dodatko | + | [[Category: Dodatko T]] |
| - | [[Category: Franklin | + | [[Category: Franklin WA]] |
| - | + | [[Category: Rajashankar KR]] | |
| - | [[Category: Rajashankar | + | [[Category: Sandigursky M]] |
| - | [[Category: Sandigursky | + | [[Category: Thirumuruhan RA]] |
| - | [[Category: Thirumuruhan | + | |
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Current revision
CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA
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