1l7b
From Proteopedia
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| - | [[Image:1l7b.gif|left|200px]]<br /><applet load="1l7b" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1l7b" /> | ||
| - | '''Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT'''<br /> | ||
| - | == | + | ==Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT== |
| - | + | <StructureSection load='1l7b' size='340' side='right'caption='[[1l7b]]' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1l7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L7B FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7b OCA], [https://pdbe.org/1l7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l7b RCSB], [https://www.ebi.ac.uk/pdbsum/1l7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l7b ProSAT], [https://www.topsan.org/Proteins/NESGC/1l7b TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/DNLJ_THET8 DNLJ_THET8] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l7/1l7b_consurf.spt"</scriptWhenChecked> |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l7b ConSurf]. |
| - | + | <div style="clear:both"></div> | |
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| - | + | ==See Also== | |
| + | *[[DNA ligase 3D structures|DNA ligase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermus thermophilus]] | ||
| + | [[Category: Anderson S]] | ||
| + | [[Category: Aramini J]] | ||
| + | [[Category: Bhattacharya D]] | ||
| + | [[Category: Dixon BL]] | ||
| + | [[Category: Huang YP]] | ||
| + | [[Category: Monleon D]] | ||
| + | [[Category: Montelione GT]] | ||
| + | [[Category: Sahota G]] | ||
| + | [[Category: Swapna GVT]] | ||
| + | [[Category: Tejero R]] | ||
| + | [[Category: Xiao R]] | ||
| + | [[Category: Yin C]] | ||
Current revision
Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT
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Categories: Large Structures | Thermus thermophilus | Anderson S | Aramini J | Bhattacharya D | Dixon BL | Huang YP | Monleon D | Montelione GT | Sahota G | Swapna GVT | Tejero R | Xiao R | Yin C
