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1zk4

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[[Image:1zk4.png|left|200px]]
 
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{{STRUCTURE_1zk4| PDB=1zk4 | SCENE= }}
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==Structure of R-specific alcohol dehydrogenase (wildtype) from Lactobacillus brevis in complex with acetophenone and NADP==
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<StructureSection load='1zk4' size='340' side='right'caption='[[1zk4]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
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===Structure of R-specific alcohol dehydrogenase (wildtype) from Lactobacillus brevis in complex with acetophenone and NADP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1zk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis Levilactobacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZK4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15896805}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC0:1-PHENYLETHANONE'>AC0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zk4 OCA], [https://pdbe.org/1zk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zk4 RCSB], [https://www.ebi.ac.uk/pdbsum/1zk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zk4 ProSAT]</span></td></tr>
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[[1zk4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis Lactobacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZK4 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q84EX5_LEVBR Q84EX5_LEVBR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/1zk4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zk4 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]
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*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015896805</ref><ref group="xtra">PMID:012628239</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Lactobacillus brevis]]
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[[Category: Levilactobacillus brevis]]
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[[Category: Hummel, W.]]
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[[Category: Hummel W]]
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[[Category: Muller, J.]]
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[[Category: Muller J]]
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[[Category: Niefind, K.]]
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[[Category: Niefind K]]
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[[Category: Riebel, B.]]
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[[Category: Riebel B]]
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[[Category: Schlieben, N H.]]
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[[Category: Schlieben NH]]
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[[Category: Schomburg, D.]]
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[[Category: Schomburg D]]
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[[Category: Magnesium dependence]]
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[[Category: Oxidoreductase]]
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[[Category: R-specific alcohol dehydrogenase]]
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[[Category: Short chain reductases/dehydrogenase]]
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Current revision

Structure of R-specific alcohol dehydrogenase (wildtype) from Lactobacillus brevis in complex with acetophenone and NADP

PDB ID 1zk4

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