2fpg

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[[Image:2fpg.png|left|200px]]
 
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{{STRUCTURE_2fpg| PDB=2fpg | SCENE= }}
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==Crystal structure of pig GTP-specific succinyl-CoA synthetase in complex with GDP==
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<StructureSection load='2fpg' size='340' side='right'caption='[[2fpg]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
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===Crystal structure of pig GTP-specific succinyl-CoA synthetase in complex with GDP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FPG FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16481318}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.96&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fpg OCA], [https://pdbe.org/2fpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fpg RCSB], [https://www.ebi.ac.uk/pdbsum/2fpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fpg ProSAT]</span></td></tr>
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[[2fpg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FPG OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SUCB2_PIG SUCB2_PIG] Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/2fpg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fpg ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Succinyl-CoA synthetase|Succinyl-CoA synthetase]]
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*[[Succinyl-CoA synthetase 3D structures|Succinyl-CoA synthetase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016481318</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Fraser, M E.]]
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[[Category: Fraser ME]]
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[[Category: Active site histidine residue]]
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[[Category: Ligase]]
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Current revision

Crystal structure of pig GTP-specific succinyl-CoA synthetase in complex with GDP

PDB ID 2fpg

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