3t5n

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[[Image:3t5n.png|left|200px]]
 
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{{STRUCTURE_3t5n| PDB=3t5n | SCENE= }}
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==1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA==
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<StructureSection load='3t5n' size='340' side='right'caption='[[3t5n]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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===1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t5n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mopeia_Lassa_virus_reassortant_29 Mopeia Lassa virus reassortant 29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T5N FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22084115}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.787&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t5n OCA], [https://pdbe.org/3t5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t5n RCSB], [https://www.ebi.ac.uk/pdbsum/3t5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t5n ProSAT]</span></td></tr>
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[[3t5n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Mopeia_lassa_reassortant_29 Mopeia lassa reassortant 29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5N OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5S585_9VIRU Q5S585_9VIRU] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses (By similarity).[PIRNR:PIRNR004029]
==See Also==
==See Also==
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*[[Nucleoprotein|Nucleoprotein]]
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*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022084115</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Mopeia lassa reassortant 29]]
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[[Category: Large Structures]]
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[[Category: Hastie, K M.]]
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[[Category: Mopeia Lassa virus reassortant 29]]
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[[Category: King, L B.]]
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[[Category: Hastie KM]]
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[[Category: Liu, T.]]
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[[Category: King LB]]
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[[Category: Ngo, N.]]
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[[Category: Liu T]]
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[[Category: Saphire, E O.]]
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[[Category: Ngo N]]
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[[Category: Torre, J C.de la.]]
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[[Category: Saphire EO]]
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[[Category: Woods, V L.]]
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[[Category: Woods VL]]
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[[Category: Zandonatti, M A.]]
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[[Category: Zandonatti MA]]
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[[Category: Single stranded rna]]
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[[Category: De la Torre JC]]
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[[Category: Ssrna]]
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[[Category: Viral protein-rna complex]]
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Current revision

1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA

PDB ID 3t5n

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