1x3k

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[[Image:1x3k.png|left|200px]]
 
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{{STRUCTURE_1x3k| PDB=1x3k | SCENE= }}
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==Crystal structure of a hemoglobin component (TA-V) from Tokunagayusurika akamusi==
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<StructureSection load='1x3k' size='340' side='right'caption='[[1x3k]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1x3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tokunagayusurika_akamusi Tokunagayusurika akamusi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X3K FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x3k OCA], [https://pdbe.org/1x3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x3k RCSB], [https://www.ebi.ac.uk/pdbsum/1x3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x3k ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7M422_9DIPT Q7M422_9DIPT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x3/1x3k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x3k ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The polymorphic components of hemoglobin (Hb) of the midge larva Propsilocerus akamusi were classified into two distinct types dependent on their spectroscopic properties, normal absorption (N) and low absorption (L). Analyses of the amino acid sequences of component VII (N-type Hb) and component V (L-type Hb) from P. akamusi indicated that one remarkable difference is the replacement of the distal histidine (His) with isoleucine (Ile) in component V. To clarify the structural differences between the two Hb components, we determined the crystal structures of components V and VII at resolutions of 1.64 A and 1.50 A, respectively. These crystal structures indicated a short additional helix comprising three amino acid residues at the C-terminal region in component V, and a typical globin fold including eight helices in component VII. Comparison of the heme regions of the Hb components suggests that the structural changes of the heme region in component V on ligation differ from that of usual Hb.
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===Crystal structure of a hemoglobin component (TA-V) from Tokunagayusurika akamusi===
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Crystal structures of two hemoglobin components from the midge larva Propsilocerus akamusi (Orthocladiinae, Diptera).,Kuwada T, Hasegawa T, Sato S, Sato I, Ishikawa K, Takagi T, Shishikura F Gene. 2007 Aug 15;398(1-2):29-34. Epub 2007 May 10. PMID:17590288<ref>PMID:17590288</ref>
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{{ABSTRACT_PUBMED_17590288}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1x3k" style="background-color:#fffaf0;"></div>
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[[1x3k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tokunagayusurika_akamusi Tokunagayusurika akamusi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X3K OCA].
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==See Also==
==See Also==
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*[[Hemoglobin|Hemoglobin]]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:017590288</ref><references group="xtra"/>
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__TOC__
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[[Category: Tokunagayusurika akamusi]]
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</StructureSection>
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[[Category: Hasegawa, T.]]
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[[Category: Large Structures]]
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[[Category: Ishikawa, K.]]
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[[Category: Kuwada, T.]]
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[[Category: Sato, I.]]
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[[Category: Sato, S.]]
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[[Category: Shishikura, F.]]
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[[Category: Takagi, T.]]
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[[Category: Diptera]]
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[[Category: Hemoglobin]]
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[[Category: Midge larva]]
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[[Category: Oxygen storage-transport complex]]
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[[Category: Tokunagayusurika akamusi]]
[[Category: Tokunagayusurika akamusi]]
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[[Category: Hasegawa T]]
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[[Category: Ishikawa K]]
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[[Category: Kuwada T]]
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[[Category: Sato I]]
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[[Category: Sato S]]
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[[Category: Shishikura F]]
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[[Category: Takagi T]]

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Crystal structure of a hemoglobin component (TA-V) from Tokunagayusurika akamusi

PDB ID 1x3k

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