2wqy

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[[Image:2wqy.png|left|200px]]
 
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{{STRUCTURE_2wqy| PDB=2wqy | SCENE= }}
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==Remodelling of carboxin binding to the Q-site of avian respiratory complex II==
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<StructureSection load='2wqy' size='340' side='right'caption='[[2wqy]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Remodelling of carboxin binding to the Q-site of avian respiratory complex II===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2wqy]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WQY FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16371358}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=BHG:2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>BHG</scene>, <scene name='pdbligand=CBE:2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE'>CBE</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqy OCA], [https://pdbe.org/2wqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wqy RCSB], [https://www.ebi.ac.uk/pdbsum/2wqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wqy ProSAT]</span></td></tr>
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[[2wqy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQY OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SDHA_CHICK SDHA_CHICK] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wq/2wqy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wqy ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Succinate Dehydrogenase|Succinate Dehydrogenase]]
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*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016371358</ref><references group="xtra"/>
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Cecchini, G.]]
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[[Category: Large Structures]]
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[[Category: Iwata, S.]]
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[[Category: Cecchini G]]
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[[Category: Ruprecht, J.]]
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[[Category: Iwata S]]
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[[Category: Complex ii]]
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[[Category: Ruprecht J]]
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[[Category: Cytocrome b]]
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[[Category: Flavoprotein]]
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[[Category: Heme protein]]
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[[Category: Iron sulfur protein]]
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[[Category: Metal-binding]]
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[[Category: Mitochondrion inner membrane]]
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[[Category: Oxaloacetate nitropropionate ubiquinone]]
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[[Category: Oxidoreductase]]
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[[Category: Redox enzyme]]
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[[Category: Respiratory chain]]
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[[Category: Tricarboxylic acid cycle]]
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Current revision

Remodelling of carboxin binding to the Q-site of avian respiratory complex II

PDB ID 2wqy

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OCA

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