3jz4

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[[Image:3jz4.png|left|200px]]
 
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{{STRUCTURE_3jz4| PDB=3jz4 | SCENE= }}
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==Crystal structure of E. coli NADP dependent enzyme==
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<StructureSection load='3jz4' size='340' side='right'caption='[[3jz4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===Crystal structure of E. coli NADP dependent enzyme===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3jz4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JZ4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20174634}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jz4 OCA], [https://pdbe.org/3jz4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jz4 RCSB], [https://www.ebi.ac.uk/pdbsum/3jz4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jz4 ProSAT]</span></td></tr>
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[[3jz4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ4 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GABD_ECOLI GABD_ECOLI] Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. It appears to be important for nitrogen metabolism under N limitation conditions.<ref>PMID:20174634</ref> <ref>PMID:7011797</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jz/3jz4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jz4 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
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*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
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*[[Succinate-semialdehyde dehydrogenase|Succinate-semialdehyde dehydrogenase]]
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==Reference==
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== References ==
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<ref group="xtra">PMID:020174634</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Buckle, A M.]]
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[[Category: Large Structures]]
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[[Category: Caradoc-Davies, T.]]
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[[Category: Buckle AM]]
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[[Category: Fenalti, G.]]
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[[Category: Caradoc-Davies T]]
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[[Category: Kan, W T.]]
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[[Category: Fenalti G]]
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[[Category: Key, T L.G.]]
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[[Category: Kan WT]]
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[[Category: Langendorf, C G.]]
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[[Category: Key TLG]]
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[[Category: Law, R H.P.]]
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[[Category: Langendorf CG]]
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[[Category: Tuck, K L.]]
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[[Category: Law RHP]]
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[[Category: Whisstock, J C.]]
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[[Category: Tuck KL]]
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[[Category: Nadp]]
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[[Category: Whisstock JC]]
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[[Category: Nadp binding]]
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[[Category: Oxidoreductase]]
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[[Category: Tetramer]]
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Current revision

Crystal structure of E. coli NADP dependent enzyme

PDB ID 3jz4

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