2fyo
From Proteopedia
(Difference between revisions)
(7 intermediate revisions not shown.) | |||
Line 1: | Line 1: | ||
- | [[Image:2fyo.png|left|200px]] | ||
- | + | ==Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212== | |
+ | <StructureSection load='2fyo' size='340' side='right'caption='[[2fyo]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[2fyo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FYO FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyo OCA], [https://pdbe.org/2fyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fyo RCSB], [https://www.ebi.ac.uk/pdbsum/2fyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fyo ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/2fyo_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fyo ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association. | ||
- | + | A monotopic membrane protein goes solo.,Mattevi A Structure. 2006 Apr;14(4):628-9. PMID:16615901<ref>PMID:16615901</ref> | |
- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | + | </div> | |
- | + | <div class="pdbe-citations 2fyo" style="background-color:#fffaf0;"></div> | |
- | + | ||
==See Also== | ==See Also== | ||
*[[Carnitine palmitoyltransferase|Carnitine palmitoyltransferase]] | *[[Carnitine palmitoyltransferase|Carnitine palmitoyltransferase]] | ||
- | + | == References == | |
- | == | + | <references/> |
- | < | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
+ | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
- | [[Category: Banner | + | [[Category: Banner DW]] |
- | [[Category: Benz | + | [[Category: Benz J]] |
- | [[Category: Chomienne | + | [[Category: Chomienne O]] |
- | [[Category: | + | [[Category: De Roo E]] |
- | [[Category: | + | [[Category: Gsell B]] |
- | [[Category: | + | [[Category: Hennig M]] |
- | [[Category: | + | [[Category: Mueller F]] |
- | [[Category: Rufer | + | [[Category: Rufer AC]] |
- | [[Category: Stihle | + | [[Category: Stihle M]] |
- | [[Category: Thoma | + | [[Category: Thoma R]] |
- | + | ||
- | + |
Current revision
Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212
|
Categories: Large Structures | Rattus norvegicus | Banner DW | Benz J | Chomienne O | De Roo E | Gsell B | Hennig M | Mueller F | Rufer AC | Stihle M | Thoma R