1n6m

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[[Image:1n6m.png|left|200px]]
 
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{{STRUCTURE_1n6m| PDB=1n6m | SCENE= }}
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==Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd==
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<StructureSection load='1n6m' size='340' side='right'caption='[[1n6m]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1n6m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N6M FirstGlance]. <br>
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{{ABSTRACT_PUBMED_14532111}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n6m OCA], [https://pdbe.org/1n6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n6m RCSB], [https://www.ebi.ac.uk/pdbsum/1n6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n6m ProSAT]</span></td></tr>
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[[1n6m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6M OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NCD_DROME NCD_DROME] NCD is required for normal chromosomal segregation in meiosis, in females, and in early mitotic divisions of the embryo. The NCD motor activity is directed toward the microtubule's minus end.<ref>PMID:2146510</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n6/1n6m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n6m ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Kinesin|Kinesin]]
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*[[Kinesin 3D Structures|Kinesin 3D Structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:014532111</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Bronner, C E.]]
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[[Category: Large Structures]]
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[[Category: Cha, S S.]]
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[[Category: Bronner CE]]
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[[Category: Endow, S A.]]
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[[Category: Cha S-S]]
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[[Category: Park, C G.]]
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[[Category: Endow SA]]
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[[Category: Park, H W.]]
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[[Category: Park C-G]]
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[[Category: Yun, M.]]
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[[Category: Park H-W]]
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[[Category: Cell cycle]]
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[[Category: Yun M]]
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[[Category: Kinesin]]
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[[Category: Microtubule]]
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[[Category: Motor]]
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[[Category: Ncd]]
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Current revision

Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd

PDB ID 1n6m

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