This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3uj4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:23, 1 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3uj4.png|left|200px]]
 
-
{{STRUCTURE_3uj4| PDB=3uj4 | SCENE= }}
+
==Crystal structure of the apo-inositol 1,4,5-trisphosphate receptor==
-
 
+
<StructureSection load='3uj4' size='340' side='right'caption='[[3uj4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
===Crystal structure of the apo-inositol 1,4,5-trisphosphate receptor===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3uj4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UJ4 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22286060}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uj4 OCA], [https://pdbe.org/3uj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uj4 RCSB], [https://www.ebi.ac.uk/pdbsum/3uj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uj4 ProSAT]</span></td></tr>
-
[[3uj4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UJ4 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ITPR1_RAT ITPR1_RAT] Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
==See Also==
==See Also==
*[[Inositol 1%2C4%2C5-Trisphosphate Receptor|Inositol 1%2C4%2C5-Trisphosphate Receptor]]
*[[Inositol 1%2C4%2C5-Trisphosphate Receptor|Inositol 1%2C4%2C5-Trisphosphate Receptor]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:022286060</ref><references group="xtra"/>
+
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
-
[[Category: Ikura, M.]]
+
[[Category: Ikura M]]
-
[[Category: Ishiyama, N.]]
+
[[Category: Ishiyama N]]
-
[[Category: Seo, M D.]]
+
[[Category: Seo MD]]
-
[[Category: Stathopulos, P.]]
+
[[Category: Stathopulos P]]
-
[[Category: 5-trisphosphate]]
+
-
[[Category: Apo-state]]
+
-
[[Category: Inositol 1]]
+
-
[[Category: Ip3-binding core domain]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Suppressor domain]]
+

Current revision

Crystal structure of the apo-inositol 1,4,5-trisphosphate receptor

PDB ID 3uj4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3uj4"
Personal tools