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2vxn

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[[Image:2vxn.png|left|200px]]
 
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{{STRUCTURE_2vxn| PDB=2vxn | SCENE= }}
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==E65Q-TIM complexed with phosphoglycolohydroxamate at 0.82 A resolution==
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<StructureSection load='2vxn' size='340' side='right'caption='[[2vxn]], [[Resolution|resolution]] 0.82&Aring;' scene=''>
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===E65Q-TIM COMPLEXED WITH PHOSPHOGLYCOLOHYDROXAMATE AT 0.82 A RESOLUTION===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2vxn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VXN FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20235230}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene>, <scene name='pdbligand=PGH:PHOSPHOGLYCOLOHYDROXAMIC+ACID'>PGH</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vxn OCA], [https://pdbe.org/2vxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vxn RCSB], [https://www.ebi.ac.uk/pdbsum/2vxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vxn ProSAT]</span></td></tr>
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[[2vxn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VXN OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPIS_LEIME TPIS_LEIME]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vx/2vxn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vxn ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
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*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020235230</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
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[[Category: Triose-phosphate isomerase]]
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[[Category: Alahuhta M]]
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[[Category: Alahuhta, M.]]
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[[Category: Wierenga RK]]
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[[Category: Wierenga, R K.]]
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[[Category: Enzyme-ligand complex]]
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[[Category: Fatty acid biosynthesis]]
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[[Category: Gluconeogenesis]]
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[[Category: Glycolysis]]
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[[Category: Glycosome]]
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[[Category: Isomerase]]
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[[Category: Lipid synthesis]]
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[[Category: Pentose shunt]]
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[[Category: Protonation state]]
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[[Category: Tim]]
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[[Category: Transition state]]
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[[Category: Transition state analogue]]
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[[Category: Triosephosphate isomerase]]
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Current revision

E65Q-TIM complexed with phosphoglycolohydroxamate at 0.82 A resolution

PDB ID 2vxn

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