1fow

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[[Image:1fow.png|left|200px]]
 
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{{STRUCTURE_1fow| PDB=1fow | SCENE= }}
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==NMR STRUCTURE OF L11-C76, THE C-TERMINAL DOMAIN OF 50S RIBOSOMAL PROTEIN L11, MINIMIZED AVERAGE STRUCTURE==
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<StructureSection load='1fow' size='340' side='right'caption='[[1fow]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FOW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fow OCA], [https://pdbe.org/1fow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fow RCSB], [https://www.ebi.ac.uk/pdbsum/1fow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fow ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RL11_GEOSE RL11_GEOSE] Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/1fow_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fow ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the C-terminal RNA recognition domain of ribosomal protein L11 has been solved by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy. Although the structure can be considered high resolution in the core, 15 residues between helix alpha 1 and strand beta 1 form an extended, unstructured loop. 15N transverse relaxation measurements suggest that the loop is moving on a picosecond-to-nanosecond time scale in the free protein but not in the protein bound to RNA. Chemical shifts differences between the free protein and the bound protein suggest that the loop as well as the C-terminal end of helix alpha 3 are involved in RNA binding.
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===NMR STRUCTURE OF L11-C76, THE C-TERMINAL DOMAIN OF 50S RIBOSOMAL PROTEIN L11, MINIMIZED AVERAGE STRUCTURE===
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High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA.,Markus MA, Hinck AP, Huang S, Draper DE, Torchia DA Nat Struct Biol. 1997 Jan;4(1):70-7. PMID:8989327<ref>PMID:8989327</ref>
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{{ABSTRACT_PUBMED_8989327}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1fow" style="background-color:#fffaf0;"></div>
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[[1fow]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FOW OCA].
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==See Also==
==See Also==
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*[[Ribosomal protein L11|Ribosomal protein L11]]
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*[[Ribosomal protein L11 3D structures|Ribosomal protein L11 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:008989327</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Draper, D E.]]
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[[Category: Large Structures]]
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[[Category: Hinck, A P.]]
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[[Category: Draper DE]]
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[[Category: Huang, S.]]
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[[Category: Hinck AP]]
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[[Category: Markus, M A.]]
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[[Category: Huang S]]
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[[Category: Torchia, D A.]]
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[[Category: Markus MA]]
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[[Category: Alpha-helical protein]]
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[[Category: Torchia DA]]
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[[Category: Homeodomain fold]]
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[[Category: L11-c76]]
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[[Category: Ribosomal protein]]
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[[Category: Rna-binding domain]]
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Current revision

NMR STRUCTURE OF L11-C76, THE C-TERMINAL DOMAIN OF 50S RIBOSOMAL PROTEIN L11, MINIMIZED AVERAGE STRUCTURE

PDB ID 1fow

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