2qrb

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[[Image:2qrb.png|left|200px]]
 
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{{STRUCTURE_2qrb| PDB=2qrb | SCENE= }}
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==Crystal structure of chloride saturated bovine lactoperoxidase at 2.5 A resolution shows multiple halide binding sites==
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<StructureSection load='2qrb' size='340' side='right'caption='[[2qrb]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal structure of chloride saturated bovine lactoperoxidase at 2.5 A resolution shows multiple halide binding sites===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2qrb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QRB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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[[2qrb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRB OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qrb OCA], [https://pdbe.org/2qrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qrb RCSB], [https://www.ebi.ac.uk/pdbsum/2qrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qrb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PERL_BOVIN PERL_BOVIN] LPO is an antimicrobial agent. It is thought to help protect the udder from infection and promote growth in newborn calves.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qr/2qrb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qrb ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Lactoperoxidase|Lactoperoxidase]]
*[[Lactoperoxidase|Lactoperoxidase]]
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__TOC__
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Peroxidase]]
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[[Category: Large Structures]]
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[[Category: Kaur, P.]]
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[[Category: Kaur P]]
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[[Category: Sharma, S.]]
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[[Category: Sharma S]]
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[[Category: Singh, A K.]]
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[[Category: Singh AK]]
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[[Category: Singh, N.]]
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[[Category: Singh N]]
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[[Category: Singh, T P.]]
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[[Category: Singh TP]]
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[[Category: Antibiotic]]
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[[Category: Antimicrobial]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Glycoprotein]]
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[[Category: Halide binding site. peroxidation]]
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[[Category: Heme]]
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[[Category: Hydrogen peroxide]]
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[[Category: Iron]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxidase]]
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[[Category: Secreted]]
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Current revision

Crystal structure of chloride saturated bovine lactoperoxidase at 2.5 A resolution shows multiple halide binding sites

PDB ID 2qrb

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