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3i11

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[[Image:3i11.png|left|200px]]
 
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{{STRUCTURE_3i11| PDB=3i11 | SCENE= }}
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==Cobalt-substituted metallo-beta-lactamase from Bacillus cereus==
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<StructureSection load='3i11' size='340' side='right'caption='[[3i11]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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===Cobalt-substituted metallo-beta-lactamase from Bacillus cereus===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3i11]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I11 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20677753}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i11 OCA], [https://pdbe.org/3i11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i11 RCSB], [https://www.ebi.ac.uk/pdbsum/3i11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i11 ProSAT]</span></td></tr>
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[[3i11]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I11 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/3i11_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i11 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020677753</ref><references group="xtra"/>
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[[Category: Bacillus cereus]]
[[Category: Bacillus cereus]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Buschiazzo, A.]]
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[[Category: Buschiazzo A]]
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[[Category: Gonzalez, J M.]]
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[[Category: Gonzalez JM]]
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[[Category: Vila, A J.]]
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[[Category: Vila AJ]]
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[[Category: Antibiotic resistance]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Metallo-beta-lactamase superfamily]]
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[[Category: Zn-dependent hydrolase]]
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Current revision

Cobalt-substituted metallo-beta-lactamase from Bacillus cereus

PDB ID 3i11

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