This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1p5d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:10, 3 April 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1p5d.png|left|200px]]
 
-
{{STRUCTURE_1p5d| PDB=1p5d | SCENE= }}
+
==Enzyme-ligand complex of P. aeruginosa PMM/PGM==
-
 
+
<StructureSection load='1p5d' size='340' side='right'caption='[[1p5d]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
===Enzyme-ligand complex of P. aeruginosa PMM/PGM===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1p5d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P5D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P5D FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_14725765}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G1P:ALPHA-D-GLUCOSE-1-PHOSPHATE'>G1P</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p5d OCA], [https://pdbe.org/1p5d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p5d RCSB], [https://www.ebi.ac.uk/pdbsum/1p5d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p5d ProSAT]</span></td></tr>
-
[[1p5d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P5D OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ALGC_PSEAE ALGC_PSEAE] The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production, an exoproduct correlated with pathogenicity, and for biofilm production.<ref>PMID:7515870</ref> <ref>PMID:10481091</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/1p5d_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p5d ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
*[[Phosphomannomutase|Phosphomannomutase]]
*[[Phosphomannomutase|Phosphomannomutase]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:014725765</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Phosphomannomutase]]
+
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
-
[[Category: Beamer, L J.]]
+
[[Category: Beamer LJ]]
-
[[Category: Regni, C.]]
+
[[Category: Regni C]]
-
[[Category: Tipton, P A.]]
+
[[Category: Tipton PA]]
-
[[Category: Alpha/beta protein]]
+
-
[[Category: Enzyme-ligand complex]]
+
-
[[Category: Enzyme-metal complex]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Phosphohexomutase]]
+
-
[[Category: Phosphoserine]]
+

Current revision

Enzyme-ligand complex of P. aeruginosa PMM/PGM

PDB ID 1p5d

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1p5d"
Personal tools