3t1y

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[[Image:3t1y.png|left|200px]]
 
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{{STRUCTURE_3t1y| PDB=3t1y | SCENE= }}
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==Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin==
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<StructureSection load='3t1y' size='340' side='right'caption='[[3t1y]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t1y]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27] and [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T1Y FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22227389}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12A:2-METHYLTHIO-N6-(AMINOCARBONYL-L-THREONYL)-ADENOSINE-5-MONOPHOSPHATE'>12A</scene>, <scene name='pdbligand=70U:5-(O-METHYLACETO)-2-THIO-2-DEOXY-URIDINE-5-MONOPHOSPHATE'>70U</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PAR:PAROMOMYCIN'>PAR</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t1y OCA], [https://pdbe.org/3t1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t1y RCSB], [https://www.ebi.ac.uk/pdbsum/3t1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t1y ProSAT]</span></td></tr>
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[[3t1y]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T1Y OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RS2_THET8 RS2_THET8] Spans the head-body hinge region of the 30S subunit. Is loosely associated with the 30S subunit.[HAMAP-Rule:MF_00291_B]
==See Also==
==See Also==
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*[[Ribosomal protein S10|Ribosomal protein S10]]
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*[[Ribosomal protein THX 3D structures|Ribosomal protein THX 3D structures]]
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*[[Ribosomal protein S11|Ribosomal protein S11]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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*[[Ribosomal protein S12|Ribosomal protein S12]]
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
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*[[Ribosomal protein S13|Ribosomal protein S13]]
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__TOC__
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*[[Ribosomal protein S14|Ribosomal protein S14]]
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</StructureSection>
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*[[Ribosomal protein S15|Ribosomal protein S15]]
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[[Category: Large Structures]]
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*[[Ribosomal protein S16|Ribosomal protein S16]]
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[[Category: Thermus thermophilus HB27]]
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*[[Ribosomal protein S17|Ribosomal protein S17]]
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[[Category: Thermus thermophilus HB8]]
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*[[Ribosomal protein S18|Ribosomal protein S18]]
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[[Category: Agris PF]]
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*[[Ribosomal protein S19|Ribosomal protein S19]]
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[[Category: Cantara W]]
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*[[Ribosomal protein S2|Ribosomal protein S2]]
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[[Category: Gustilo EM]]
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*[[Ribosomal protein S20|Ribosomal protein S20]]
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[[Category: Leszczynska G]]
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*[[Ribosomal protein S3|Ribosomal protein S3]]
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[[Category: Malkiewicz AAP]]
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*[[Ribosomal protein S4|Ribosomal protein S4]]
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[[Category: Murphy FV]]
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*[[Ribosomal protein S5|Ribosomal protein S5]]
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[[Category: Sproat B]]
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*[[Ribosomal protein S6|Ribosomal protein S6]]
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[[Category: Vendeix FAP]]
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*[[Ribosomal protein S7|Ribosomal protein S7]]
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*[[Ribosomal protein S8|Ribosomal protein S8]]
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*[[Ribosomal protein S9|Ribosomal protein S9]]
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*[[Ribosomal protein THX|Ribosomal protein THX]]
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==Reference==
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<ref group="xtra">PMID:022227389</ref><references group="xtra"/>
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[[Category: Thermus thermophilus]]
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[[Category: Agris, P F.]]
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[[Category: Cantara, W.]]
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[[Category: Gustilo, E M.]]
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[[Category: Leszczynska, G.]]
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[[Category: Malkiewicz, A A.P.]]
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[[Category: Murphy, F V.]]
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[[Category: Sproat, B.]]
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[[Category: Vendeix, F A.P.]]
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[[Category: Protein synthesis]]
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[[Category: Ribosome-antibiotic complex]]
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[[Category: Trna]]
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Current revision

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin

PDB ID 3t1y

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