1evf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:06, 20 March 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1evf.png|left|200px]]
 
-
{{STRUCTURE_1evf| PDB=1evf | SCENE= }}
+
==CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI==
-
 
+
<StructureSection load='1evf' size='340' side='right'caption='[[1evf]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
===CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1evf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVF FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_10841779}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CXM:N-CARBOXYMETHIONINE'>CXM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evf OCA], [https://pdbe.org/1evf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evf RCSB], [https://www.ebi.ac.uk/pdbsum/1evf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evf ProSAT]</span></td></tr>
-
[[1evf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVF OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_ECOLI TYSY_ECOLI] Provides the sole de novo source of dTMP for DNA biosynthesis. This protein also binds to its mRNA thus repressing its own translation.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/1evf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1evf ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Thymidylate synthase|Thymidylate synthase]]
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:010841779</ref><references group="xtra"/>
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Thymidylate synthase]]
+
[[Category: Large Structures]]
-
[[Category: Berger, S.]]
+
[[Category: Berger S]]
-
[[Category: Dunlap, R B.]]
+
[[Category: Dunlap RB]]
-
[[Category: Lebioda, L.]]
+
[[Category: Lebioda L]]
-
[[Category: Mahdavian, E.]]
+
[[Category: Mahdavian E]]
-
[[Category: Minor, W.]]
+
[[Category: Minor W]]
-
[[Category: Nivens, M C.]]
+
[[Category: Nivens MC]]
-
[[Category: Phan, J.]]
+
[[Category: Phan J]]
-
[[Category: Spencer, H T.]]
+
[[Category: Spencer HT]]
-
[[Category: Thr167 e. coli thymidylate synthase]]
+
-
[[Category: Transferase]]
+

Current revision

CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI

PDB ID 1evf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1evf"
Personal tools