3gel

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[[Image:3gel.png|left|200px]]
 
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{{STRUCTURE_3gel| PDB=3gel | SCENE= }}
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==O-Methylphosphorylated Torpedo Acetylcholinesterase Obtained by Reaction with Methyl Paraoxon (AGED)==
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<StructureSection load='3gel' size='340' side='right'caption='[[3gel]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
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===O-Methylphosphorylated Torpedo Acetylcholinesterase Obtained by Reaction with Methyl Paraoxon (AGED)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3gel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OMH:O-[(S)-HYDROXY(METHOXY)PHOSPHORYL]-L-SERINE'>OMH</scene></td></tr>
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[[3gel]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEL OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gel OCA], [https://pdbe.org/3gel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gel RCSB], [https://www.ebi.ac.uk/pdbsum/3gel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gel ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/3gel_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gel ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Acetylcholinesterase|Acetylcholinesterase]]
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*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
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[[Category: Acetylcholinesterase]]
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__TOC__
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[[Category: Torpedo californica]]
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</StructureSection>
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[[Category: Legler, P M.]]
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[[Category: Large Structures]]
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[[Category: Millard, C B.]]
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[[Category: Tetronarce californica]]
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[[Category: Hydrolase]]
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[[Category: Legler PM]]
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[[Category: Methyl paraoxon]]
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[[Category: Millard CB]]
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[[Category: Neurotransmitter degradation]]
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[[Category: Serine esterase]]
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[[Category: Synapse]]
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Current revision

O-Methylphosphorylated Torpedo Acetylcholinesterase Obtained by Reaction with Methyl Paraoxon (AGED)

PDB ID 3gel

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