3q67

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[[Image:3q67.png|left|200px]]
 
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{{STRUCTURE_3q67| PDB=3q67 | SCENE= }}
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==Human Aldose Reductase C298S mutant in Complex with NADP+ in Space Group P212121==
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<StructureSection load='3q67' size='340' side='right'caption='[[3q67]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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===Human Aldose Reductase C298S mutant in Complex with NADP+ in Space Group P212121===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3q67]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q67 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q67 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21084309}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q67 OCA], [https://pdbe.org/3q67 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q67 RCSB], [https://www.ebi.ac.uk/pdbsum/3q67 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q67 ProSAT]</span></td></tr>
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[[3q67]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q67 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
==See Also==
==See Also==
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*[[Aldose Reductase|Aldose Reductase]]
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*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021084309</ref><references group="xtra"/>
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[[Category: Aldehyde reductase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Balendiran, G K.]]
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[[Category: Large Structures]]
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[[Category: Cascio, D.]]
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[[Category: Balendiran GK]]
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[[Category: Sawaya, M R.]]
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[[Category: Cascio D]]
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[[Category: Alpha/beta barrel]]
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[[Category: Sawaya MR]]
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[[Category: Oxidoreductase]]
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Current revision

Human Aldose Reductase C298S mutant in Complex with NADP+ in Space Group P212121

PDB ID 3q67

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