3sm4

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[[Image:3sm4.png|left|200px]]
 
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{{STRUCTURE_3sm4| PDB=3sm4 | SCENE= }}
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==Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium==
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<StructureSection load='3sm4' size='340' side='right'caption='[[3sm4]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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===Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sm4]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SM4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21730170}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sm4 OCA], [https://pdbe.org/3sm4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sm4 RCSB], [https://www.ebi.ac.uk/pdbsum/3sm4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sm4 ProSAT]</span></td></tr>
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[[3sm4]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SM4 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EXO_LAMBD EXO_LAMBD] Facilitates phage DNA recombination through the double-strand break repair (DSBR) and single-strand annealing pathways. Also important for the late, rolling-circle mode of lambda DNA replication.
==See Also==
==See Also==
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*[[Exonuclease|Exonuclease]]
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*[[Exonuclease 3D structures|Exonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021730170</ref><references group="xtra"/>
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[[Category: Escherichia virus Lambda]]
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[[Category: Enterobacteria phage lambda]]
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[[Category: Large Structures]]
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[[Category: Bell, C E.]]
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[[Category: Bell CE]]
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[[Category: Zhang, J.]]
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[[Category: Zhang J]]
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[[Category: 5'-3' dsdna exonuclease]]
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[[Category: Dna repair]]
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[[Category: Homologous recombination]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Recombineering]]
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[[Category: Single-strand annealing]]
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[[Category: Type ii restriction endonuclease fold]]
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Current revision

Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium

PDB ID 3sm4

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