2e2y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:34, 25 October 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2e2y.png|left|200px]]
 
-
{{STRUCTURE_2e2y| PDB=2e2y | SCENE= }}
+
==Crystal Structure of F43W/H64D/V68I Myoglobin==
 +
<StructureSection load='2e2y' size='340' side='right'caption='[[2e2y]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2e2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E2Y FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e2y OCA], [https://pdbe.org/2e2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e2y RCSB], [https://www.ebi.ac.uk/pdbsum/2e2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e2y ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/2e2y_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e2y ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
A series of myoglobin mutants, in which distal sites are modified by site-directed mutagenesis, are able to catalyze peroxidase, catalase, and P450 reactions even though their proximal histidine ligands are intact. More importantly, reactions of P450, catalase, and peroxidase substrates and compound I of myoglobin mutants can be observed spectroscopically. Thus, detailed oxidation mechanisms were examined. On the basis of these results, we suggest that the different reactivities of P450, catalase, and peroxidase are mainly caused by their active site structures, but not the axial ligand. We have also prepared compound 0 under physiological conditions by employing a mutant of cytochrome c 552. Compound 0 is not able to oxidize ascorbic acid.
-
===Crystal Structure of F43W/H64D/V68I Myoglobin===
+
Reactivities of oxo and peroxo intermediates studied by hemoprotein mutants.,Watanabe Y, Nakajima H, Ueno T Acc Chem Res. 2007 Jul;40(7):554-62. Epub 2007 Jun 14. PMID:17567089<ref>PMID:17567089</ref>
-
{{ABSTRACT_PUBMED_17567089}}
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
==About this Structure==
+
<div class="pdbe-citations 2e2y" style="background-color:#fffaf0;"></div>
-
[[2e2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E2Y OCA].
+
==See Also==
==See Also==
-
*[[Myoglobin|Myoglobin]]
+
*[[Myoglobin 3D structures|Myoglobin 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:017567089</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Physeter catodon]]
[[Category: Physeter catodon]]
-
[[Category: Hikage, T.]]
+
[[Category: Hikage T]]
-
[[Category: Ohki, T.]]
+
[[Category: Ohki T]]
-
[[Category: Suzuki, A.]]
+
[[Category: Suzuki A]]
-
[[Category: Ueno, T.]]
+
[[Category: Ueno T]]
-
[[Category: Watanabe, Y.]]
+
[[Category: Watanabe Y]]
-
[[Category: Yamane, T.]]
+
[[Category: Yamane T]]
-
[[Category: Oxygen storage-transport complex]]
+
-
[[Category: Oxygen storage/transport]]
+

Current revision

Crystal Structure of F43W/H64D/V68I Myoglobin

PDB ID 2e2y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2e2y"
Personal tools