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2uyr

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[[Image:2uyr.png|left|200px]]
 
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{{STRUCTURE_2uyr| PDB=2uyr | SCENE= }}
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==Crystal structure of Bacillus cereus sphingomyelinase mutant :N57A==
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<StructureSection load='2uyr' size='340' side='right'caption='[[2uyr]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF BACILLUS CEREUS SPHINGOMYELINASE MUTANT :N57A===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2uyr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UYR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[2uyr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYR OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyr OCA], [https://pdbe.org/2uyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uyr RCSB], [https://www.ebi.ac.uk/pdbsum/2uyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHL2_BACCE PHL2_BACCE] Required, with sphingomyelinase, to effect target cell lysis (hemolysis).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uyr ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Sphingomyelinase|Sphingomyelinase]]
*[[Sphingomyelinase|Sphingomyelinase]]
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__TOC__
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</StructureSection>
[[Category: Bacillus cereus]]
[[Category: Bacillus cereus]]
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[[Category: Sphingomyelin phosphodiesterase]]
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[[Category: Large Structures]]
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[[Category: Oda, M.]]
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[[Category: Oda M]]
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[[Category: Sakurai, J.]]
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[[Category: Sakurai J]]
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[[Category: Tsuge, H.]]
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[[Category: Tsuge H]]
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[[Category: Bacillus cereus sphingomyelinase]]
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[[Category: Cytolysis]]
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[[Category: Hemolysis]]
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[[Category: Hydrolase]]
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[[Category: N57a metal ion of side-edge]]
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Current revision

Crystal structure of Bacillus cereus sphingomyelinase mutant :N57A

PDB ID 2uyr

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