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1nag

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[[Image:1nag.png|left|200px]]
 
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{{STRUCTURE_1nag| PDB=1nag | SCENE= }}
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==CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A==
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<StructureSection load='1nag' size='340' side='right'caption='[[1nag]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1nag]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NAG FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8518731}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nag OCA], [https://pdbe.org/1nag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nag RCSB], [https://www.ebi.ac.uk/pdbsum/1nag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nag ProSAT]</span></td></tr>
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[[1nag]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAG OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BPT1_BOVIN BPT1_BOVIN] Inhibits trypsin, kallikrein, chymotrypsin, and plasmin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/1nag_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nag ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Basic Pancreatic Trypsin Inhibitor|Basic Pancreatic Trypsin Inhibitor]]
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*[[BPTI 3D structures|BPTI 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008518731</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Danishefsky, A T.]]
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[[Category: Large Structures]]
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[[Category: Kim, K S.]]
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[[Category: Danishefsky AT]]
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[[Category: Tao, F.]]
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[[Category: Kim K-S]]
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[[Category: Wlodawer, A.]]
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[[Category: Tao F]]
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[[Category: Woodward, C.]]
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[[Category: Wlodawer A]]
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[[Category: Serine protease inhibitor]]
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[[Category: Woodward C]]

Current revision

CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A

PDB ID 1nag

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