1nkd

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[[Image:1nkd.png|left|200px]]
 
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{{STRUCTURE_1nkd| PDB=1nkd | SCENE= }}
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==ATOMIC RESOLUTION (1.07 ANGSTROMS) STRUCTURE OF THE ROP MUTANT <2AA>==
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<StructureSection load='1nkd' size='340' side='right'caption='[[1nkd]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
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===ATOMIC RESOLUTION (1.07 ANGSTROMS) STRUCTURE OF THE ROP MUTANT <2AA>===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1nkd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NKD FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10089502}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nkd OCA], [https://pdbe.org/1nkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nkd RCSB], [https://www.ebi.ac.uk/pdbsum/1nkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nkd ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1nkd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKD OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/1nkd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nkd ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Rop protein|Rop protein]]
*[[Rop protein|Rop protein]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010089502</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Kokkinidis, M.]]
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[[Category: Large Structures]]
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[[Category: Vlassi, M.]]
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[[Category: Kokkinidis M]]
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[[Category: 4-alpha-helix bundle]]
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[[Category: Vlassi M]]
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[[Category: Atomic resolution structure]]
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[[Category: Transcription regulation]]
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ATOMIC RESOLUTION (1.07 ANGSTROMS) STRUCTURE OF THE ROP MUTANT <2AA>

PDB ID 1nkd

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