1xl6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:07, 25 October 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1xl6.png|left|200px]]
 
-
{{STRUCTURE_1xl6| PDB=1xl6 | SCENE= }}
+
==Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1==
-
 
+
<StructureSection load='1xl6' size='340' side='right'caption='[[1xl6]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
-
===Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1xl6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XL6 FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
-
[[1xl6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL6 OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xl6 OCA], [https://pdbe.org/1xl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xl6 RCSB], [https://www.ebi.ac.uk/pdbsum/1xl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xl6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xl/1xl6_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xl6 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Potassium Channel|Potassium Channel]]
+
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Magnetospirillum magnetotacticum]]
[[Category: Magnetospirillum magnetotacticum]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Doyle, D A.]]
+
[[Category: Doyle DA]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Gulbis, J M.]]
+
[[Category: Gulbis JM]]
-
[[Category: Kuo, A.]]
+
[[Category: Kuo A]]
-
[[Category: Smith, B.]]
+
[[Category: Smith B]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Sundstrom M]]
-
[[Category: Integral membrane protein]]
+
-
[[Category: Inwardly rectifying k+ channel]]
+
-
[[Category: Ion channel]]
+
-
[[Category: Metal transport]]
+

Current revision

Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1

PDB ID 1xl6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xl6"
Personal tools