1tfk

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[[Image:1tfk.png|left|200px]]
 
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{{STRUCTURE_1tfk| PDB=1tfk | SCENE= }}
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==Ribonuclease from Escherichia coli complexed with its inhibtor protein==
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<StructureSection load='1tfk' size='340' side='right'caption='[[1tfk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Ribonuclease from Escherichia coli complexed with its inhibtor protein===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tfk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TFK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15336558}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tfk OCA], [https://pdbe.org/1tfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tfk RCSB], [https://www.ebi.ac.uk/pdbsum/1tfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tfk ProSAT]</span></td></tr>
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[[1tfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFK OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CEAD_ECOLX CEAD_ECOLX] Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. Colicin D inhibits protein synthesis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tf/1tfk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tfk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Colicin|Colicin]]
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*[[Colicin 3D structures|Colicin 3D structures]]
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*[[Colicin Immunity Protein|Colicin Immunity Protein]]
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*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015336558</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Hidaka, M.]]
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[[Category: Large Structures]]
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[[Category: Kezuka, Y.]]
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[[Category: Hidaka M]]
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[[Category: Masaki, H.]]
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[[Category: Kezuka Y]]
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[[Category: Nakanishi, K.]]
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[[Category: Masaki H]]
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[[Category: Nonaka, T.]]
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[[Category: Nakanishi K]]
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[[Category: Ogawa, T.]]
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[[Category: Nonaka T]]
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[[Category: Ohsawa, K.]]
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[[Category: Ogawa T]]
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[[Category: Takahashi, K.]]
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[[Category: Ohsawa K]]
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[[Category: Yajima, S.]]
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[[Category: Takahashi K]]
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[[Category: Protein-protein complex]]
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[[Category: Yajima S]]
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[[Category: Toxin-toxin inhibitor complex]]
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Current revision

Ribonuclease from Escherichia coli complexed with its inhibtor protein

PDB ID 1tfk

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