This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3nkh
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3nkh.png|left|200px]] | ||
| - | + | ==Crystal Structure of Integrase from MRSA strain Staphylococcus aureus== | |
| - | + | <StructureSection load='3nkh' size='340' side='right' caption='[[3nkh]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3nkh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staat Staat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NKH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[3nkh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">USA300HOU_0850 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=451516 STAAT])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nkh OCA], [http://pdbe.org/3nkh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nkh RCSB], [http://www.ebi.ac.uk/pdbsum/3nkh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nkh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/3nkh_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nkh ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| + | *[[Integrase|Integrase]] | ||
*[[Retroviral Integrase|Retroviral Integrase]] | *[[Retroviral Integrase|Retroviral Integrase]] | ||
| - | [[Category: | + | __TOC__ |
| - | [[Category: Gornicki, P | + | </StructureSection> |
| - | [[Category: Joachimiak, A | + | [[Category: Staat]] |
| - | [[Category: Kim, Y | + | [[Category: Gornicki, P]] |
| - | [[Category: | + | [[Category: Joachimiak, A]] |
| - | [[Category: Tesar, C | + | [[Category: Kim, Y]] |
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tesar, C]] | ||
[[Category: Alpha-fold]] | [[Category: Alpha-fold]] | ||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
| - | [[Category: Midwest center for structural genomic]] | ||
[[Category: Mrsa protein]] | [[Category: Mrsa protein]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Recombination]] | [[Category: Recombination]] | ||
| - | [[Category: Structural genomic]] | ||
Current revision
Crystal Structure of Integrase from MRSA strain Staphylococcus aureus
| |||||||||||
