1fa6

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[[Image:1fa6.png|left|200px]]
 
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{{STRUCTURE_1fa6| PDB=1fa6 | SCENE= }}
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==CRYSTAL STRUCTURE OF THE CO(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI==
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<StructureSection load='1fa6' size='340' side='right'caption='[[1fa6]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE CO(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fa6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FA6 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10913283}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fa6 OCA], [https://pdbe.org/1fa6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fa6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fa6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fa6 ProSAT]</span></td></tr>
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[[1fa6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FA6 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LGUL_ECOLI LGUL_ECOLI] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.<ref>PMID:10913283</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fa/1fa6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fa6 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Glyoxalase|Glyoxalase]]
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*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010913283</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Lactoylglutathione lyase]]
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[[Category: Large Structures]]
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[[Category: Clugston, S L.]]
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[[Category: Clugston SL]]
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[[Category: He, M M.]]
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[[Category: He MM]]
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[[Category: Honek, J F.]]
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[[Category: Honek JF]]
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[[Category: Matthews, B W.]]
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[[Category: Matthews BW]]
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[[Category: Beta-alpha-beta-beta-beta motif]]
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[[Category: Homodimer]]
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[[Category: Lyase]]
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Current revision

CRYSTAL STRUCTURE OF THE CO(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI

PDB ID 1fa6

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