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2kwp

From Proteopedia

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[[Image:2kwp.png|left|200px]]
 
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{{STRUCTURE_2kwp| PDB=2kwp | SCENE= }}
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==Solution structure of the aminoterminal domain of E. coli NusA==
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<StructureSection load='2kwp' size='340' side='right'caption='[[2kwp]]' scene=''>
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===Solution structure of the aminoterminal domain of E. coli NusA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2kwp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KWP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kwp OCA], [https://pdbe.org/2kwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kwp RCSB], [https://www.ebi.ac.uk/pdbsum/2kwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kwp ProSAT]</span></td></tr>
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[[2kwp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KWP OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NUSA_ECOLI NUSA_ECOLI] Participates in both transcription termination and antitermination. Involved in a variety of cellular and viral termination and antitermination processes, such as Rho-dependent transcriptional termination, intrinsic termination, and phage lambda N-mediated transcriptional antitermination. Also important for coordinating the cellular responses to DNA damage by coupling the processes of nucleotide excision repair and translesion synthesis to transcription.<ref>PMID:6263495</ref> <ref>PMID:6265785</ref> <ref>PMID:6199039</ref> <ref>PMID:2821282</ref> <ref>PMID:7536848</ref> <ref>PMID:9139668</ref> <ref>PMID:11719185</ref> <ref>PMID:20696893</ref> <ref>PMID:21922055</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/2kwp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kwp ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Elongation factor|Elongation factor]]
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
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[[Category: Escherichia coli]]
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== References ==
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[[Category: Jurk, M.]]
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<references/>
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[[Category: Roesch, P.]]
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__TOC__
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[[Category: Schweimer, K.]]
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</StructureSection>
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[[Category: Nusa]]
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[[Category: Escherichia coli K-12]]
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[[Category: Transcription]]
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[[Category: Large Structures]]
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[[Category: Jurk M]]
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[[Category: Roesch P]]
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[[Category: Schweimer K]]

Current revision

Solution structure of the aminoterminal domain of E. coli NusA

PDB ID 2kwp

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