3ltq

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[[Image:3ltq.png|left|200px]]
 
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{{STRUCTURE_3ltq| PDB=3ltq | SCENE= }}
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==Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag==
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<StructureSection load='3ltq' size='340' side='right'caption='[[3ltq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ltq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LTQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LTQ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21182275}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TB:TERBIUM(III)+ION'>TB</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ltq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ltq OCA], [https://pdbe.org/3ltq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ltq RCSB], [https://www.ebi.ac.uk/pdbsum/3ltq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ltq ProSAT]</span></td></tr>
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[[3ltq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LTQ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref>
==See Also==
==See Also==
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*[[Interleukin|Interleukin]]
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*[[Interleukin 3D structures|Interleukin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021182275</ref><ref group="xtra">PMID:017497863</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Allen, K N.]]
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[[Category: Large Structures]]
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[[Category: Peisach, E.]]
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[[Category: Allen KN]]
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[[Category: Cytokine]]
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[[Category: Peisach E]]
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[[Category: Il1b]]
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[[Category: Inflammatory response]]
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[[Category: Lanthanide binding tag]]
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[[Category: Lbt]]
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[[Category: Mitogen]]
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[[Category: Pyrogen]]
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[[Category: Secreted]]
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[[Category: Terbium]]
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Current revision

Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag

PDB ID 3ltq

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