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2zit

From Proteopedia

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[[Image:2zit.png|left|200px]]
 
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{{STRUCTURE_2zit| PDB=2zit | SCENE= }}
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==Structure of the eEF2-ExoA-NAD+ complex==
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<StructureSection load='2zit' size='340' side='right'caption='[[2zit]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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===Structure of the eEF2-ExoA-NAD+ complex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2zit]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZIT FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18583986}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DDE:{3-[4-(2-AMINO-2-CARBOXY-ETHYL)-1H-IMIDAZOL-2-YL]-1-CARBAMOYL-PROPYL}-TRIMETHYL-AMMONIUM'>DDE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zit OCA], [https://pdbe.org/2zit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zit RCSB], [https://www.ebi.ac.uk/pdbsum/2zit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zit ProSAT]</span></td></tr>
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[[2zit]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIT OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EF2_YEAST EF2_YEAST]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zi/2zit_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zit ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Elongation factor|Elongation factor]]
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
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*[[Exotoxin 3D structures|Exotoxin 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:018583986</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Jorgensen, R.]]
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[[Category: Jorgensen R]]
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[[Category: Merrill, A R.]]
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[[Category: Merrill AR]]
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[[Category: Adp-ribosylation]]
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[[Category: Biosynthetic protein-transferase complex]]
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[[Category: Elongation factor]]
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[[Category: Glycosyltransferase]]
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[[Category: Gtp-binding]]
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[[Category: Nad]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Protein biosynthesis]]
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[[Category: Rna-binding]]
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[[Category: Rrna-binding]]
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[[Category: Toxin]]
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[[Category: Toxin-substrate complex]]
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[[Category: Transferase]]
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Current revision

Structure of the eEF2-ExoA-NAD+ complex

PDB ID 2zit

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