4dyu
From Proteopedia
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| - | [[Image:4dyu.png|left|200px]] | ||
| - | + | ==The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10== | |
| - | + | <StructureSection load='4dyu' size='340' side='right'caption='[[4dyu]], [[Resolution|resolution]] 2.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4dyu]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_KIM10+ Yersinia pestis KIM10+]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DYU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[4dyu]] is a 12 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dyu OCA], [https://pdbe.org/4dyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dyu RCSB], [https://www.ebi.ac.uk/pdbsum/4dyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dyu ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPS_YERPE DPS_YERPE] During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.[HAMAP-Rule:MF_01441] | ||
==See Also== | ==See Also== | ||
| - | *[[Ferritin|Ferritin]] | + | *[[Ferritin 3D structures|Ferritin 3D structures]] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Gu | + | [[Category: Yersinia pestis KIM10+]] |
| - | [[Category: Joachimiak | + | [[Category: Anderson WF]] |
| - | [[Category: Kwon | + | [[Category: Gu M]] |
| - | [[Category: Tan | + | [[Category: Joachimiak A]] |
| - | + | [[Category: Kwon K]] | |
| - | + | [[Category: Tan K]] | |
| - | + | ||
| - | + | ||
Current revision
The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10
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