2w4e
From Proteopedia
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| - | [[Image:2w4e.png|left|200px]] | ||
| - | + | ==Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans== | |
| + | <StructureSection load='2w4e' size='340' side='right'caption='[[2w4e]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2w4e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W4E FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4e OCA], [https://pdbe.org/2w4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w4e RCSB], [https://www.ebi.ac.uk/pdbsum/2w4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4e ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9RSC1_DEIRA Q9RSC1_DEIRA] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/2w4e_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w4e ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Nudix pyrophosphatases are a well represented protein family in the Deinococcus radiodurans genome. These hydrolases, which are known to be enzymatically active towards nucleoside diphosphate derivatives, play a role in cleansing the cell pool of potentially deleterious damage products. Here, the structure of DR2204, the only ADP-ribose pyrophosphatase in the D. radiodurans genome that is known to be active towards flavin adenosine dinucleotide (FAD), is presented at 2.0 angstrom resolution. | ||
| - | + | Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans.,Goncalves AM, Fioravanti E, Stelter M, McSweeney S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 1;65(Pt, 11):1083-7. Epub 2009 Oct 13. PMID:19923723<ref>PMID:19923723</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2w4e" style="background-color:#fffaf0;"></div> | |
| - | + | ||
==See Also== | ==See Also== | ||
| - | *[[ADP-ribose pyrophosphatase|ADP-ribose pyrophosphatase]] | + | *[[ADP-ribose pyrophosphatase 3D structures|ADP-ribose pyrophosphatase 3D structures]] |
| - | + | *[[Nudix hydrolase 3D structures|Nudix hydrolase 3D structures]] | |
| - | == | + | == References == |
| - | < | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Fioravanti | + | [[Category: Deinococcus radiodurans R1]] |
| - | [[Category: Goncalves | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fioravanti E]] |
| - | [[Category: Stelter | + | [[Category: Goncalves AMD]] |
| - | + | [[Category: McSweeney S]] | |
| - | + | [[Category: Stelter M]] | |
Current revision
Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans
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