1mh2

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[[Image:1mh2.jpg|left|200px]]<br /><applet load="1mh2" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1mh2, resolution 2.70&Aring;" />
 
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'''Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)'''<br />
 
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==About this Structure==
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==Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)==
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1MH2 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH2 OCA].
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<StructureSection load='1mh2' size='340' side='right'caption='[[1mh2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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[[Category: Naja sagittifera]]
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== Structural highlights ==
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[[Category: Phospholipase A(2)]]
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<table><tr><td colspan='2'>[[1mh2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MH2 FirstGlance]. <br>
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[[Category: Protein complex]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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[[Category: Jabeen, T.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Paramasivam, M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mh2 OCA], [https://pdbe.org/1mh2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mh2 RCSB], [https://www.ebi.ac.uk/pdbsum/1mh2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mh2 ProSAT]</span></td></tr>
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[[Category: Sharma, S.]]
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</table>
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[[Category: Singh, N.]]
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== Function ==
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[[Category: Singh, R K.]]
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[https://www.uniprot.org/uniprot/PA2B1_NAJSG PA2B1_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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[[Category: Singh, T P.]]
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== Evolutionary Conservation ==
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[[Category: Srinivasan, A.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Varma, A K.]]
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Check<jmol>
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[[Category: ACY]]
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<jmolCheckbox>
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[[Category: ZN]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/1mh2_consurf.spt"</scriptWhenChecked>
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[[Category: complex]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: enzyme]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: phospholipase a2]]
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</jmolCheckbox>
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[[Category: phospholipids]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mh2 ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:55:10 2008''
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==See Also==
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Naja sagittifera]]
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[[Category: Jabeen T]]
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[[Category: Paramasivam M]]
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[[Category: Sharma S]]
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[[Category: Singh N]]
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[[Category: Singh RK]]
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[[Category: Singh TP]]
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[[Category: Srinivasan A]]
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[[Category: Varma AK]]

Current revision

Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)

PDB ID 1mh2

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