2luv
From Proteopedia
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- | [[Image:2luv.png|left|200px]] | ||
- | + | ==Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin== | |
- | + | <StructureSection load='2luv' size='340' side='right'caption='[[2luv]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2luv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUV FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2luv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luv OCA], [https://pdbe.org/2luv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2luv RCSB], [https://www.ebi.ac.uk/pdbsum/2luv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2luv ProSAT]</span></td></tr> |
- | [[2luv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUV OCA]. | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ITAX_HUMAN ITAX_HUMAN] Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. | ||
==See Also== | ==See Also== | ||
- | *[[Integrin|Integrin]] | + | *[[Integrin 3D structures|Integrin 3D structures]] |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Bhattacharjya S]] |
- | [[Category: | + | [[Category: Chua GL]] |
- | [[Category: | + | [[Category: Patra TA]] |
- | [[Category: | + | [[Category: Tan SM]] |
+ | [[Category: Tang X]] |
Current revision
Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
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Categories: Homo sapiens | Large Structures | Bhattacharjya S | Chua GL | Patra TA | Tan SM | Tang X