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3dre

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[[Image:3dre.png|left|200px]]
 
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{{STRUCTURE_3dre| PDB=3dre | SCENE= }}
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==Crystal structure of Human Brain-type Creatine Kinase==
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<StructureSection load='3dre' size='340' side='right'caption='[[3dre]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===Crystal structure of Human Brain-type Creatine Kinase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3dre]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18977227}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dre OCA], [https://pdbe.org/3dre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dre RCSB], [https://www.ebi.ac.uk/pdbsum/3dre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dre ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3dre]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRE OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/KCRB_HUMAN KCRB_HUMAN] Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/3dre_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dre ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Creatine Kinase|Creatine Kinase]]
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*[[Creatine kinase 3D structures|Creatine kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:018977227</ref><references group="xtra"/>
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[[Category: Creatine kinase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bong, S M.]]
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[[Category: Large Structures]]
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[[Category: Chi, Y M.]]
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[[Category: Bong SM]]
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[[Category: Hwang, K Y.]]
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[[Category: Chi YM]]
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[[Category: Moon, J H.]]
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[[Category: Hwang KY]]
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[[Category: Atp-binding]]
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[[Category: Moon JH]]
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[[Category: Creatine kinase]]
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[[Category: Human]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Human Brain-type Creatine Kinase

PDB ID 3dre

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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