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1avg
From Proteopedia
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| - | [[Image:1avg.png|left|200px]] | ||
| - | + | ==THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS== | |
| - | + | <StructureSection load='1avg' size='340' side='right'caption='[[1avg]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1avg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Meccus_pallidipennis Meccus pallidipennis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AVG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1avg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1avg OCA], [https://pdbe.org/1avg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1avg RCSB], [https://www.ebi.ac.uk/pdbsum/1avg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1avg ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1avg]] is a 3 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/av/1avg_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1avg ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Thrombin|Thrombin]] | + | *[[Thrombin 3D Structures|Thrombin 3D Structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Meccus pallidipennis]] |
| - | [[Category: Bode | + | [[Category: Bode W]] |
| - | [[Category: Fuentes-Prior | + | [[Category: Fuentes-Prior P]] |
| - | [[Category: Huber | + | [[Category: Huber R]] |
| - | + | ||
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Current revision
THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS
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